NIH R01 · 2024
Genomic discovery and prediction for quantitative traits with complex genetic mechanisms
Program Director/Principal Investigator (Da, Yang): Project Description MOTIVATION AND OBJECTIVES Complex genetic mechanism of quantitative traits may include gene interaction effects commonly referred to as epistasis and multiple genetic factors with small effects. This is among the most difficult genetic areas due to difficulties to discover and the need of large samples to detect many small effects. The U.S. Holstein cattle have the largest genomic evaluation program in the world with 3,852,580 genotyped cattle by March 2021, and the number of genotyped cattle increased at a pace of ~600,000 per year. Among the genotyped cows, phenotypic records were available for 43 traits covering…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.