D'souza Lab

Yale University

PSYCHIATRY

New Haven · United States

NIH-funded
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NIH R01 · 2024

Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans

Abstract As legalization of cannabis, whether for recreational or medical use, rapidly spreads in the United States, it is acutely necessary to study it. Environmental factors play a role in the development of cannabis use disorder (CanUD), but less is known about the genetic basis of the risk for developing CanUD, its short- and long-term effects, the individual's response to cannabis derivatives such as cannabidiol (CBD), and the individual's response to new treatments for CanUD. Because people of many different ancestries use cannabis, genetic analyses must include non-European populations, including African ancestry, East Asian, and admixed American (Latino). Our group published the…

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