NIH R01 · 2024
High Sensitivity Diffuse Optical Tomography of Human Brain Funciton
Project Summary: This grant will develop speckle contrast optical tomography (SCOT) for imaging of cerebral blood flow dynamics in humans. Real-time maps of cerebral blood flow (CBF) at the bedside are a long sought-after assay for neuro-critical care. Most critically, regional CBF measures can indicate which brain regions may be becoming ischemic and are at danger for hypoxic-ischemic injury. Current clinical methods for imaging CBF include positron emission tomography (PET) and arterial spin labeling with Magnetic Resonance Imaging (ASL- MRI). Both modalities provide only snapshots of CBF, though, thus they miss dynamic events, which are important in many clinical scenarios including…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.