Cullen Lab

Johns Hopkins University

BIOMEDICAL ENGINEERING

Baltimore · United States

NIH-funded
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NIH R01 · 2025

Neural Computations Underlying Cancellation of the Vestibular Consequences of Voluntary Movement

Project Summary: This research program is motivated by three goals. First, we will establish the cerebellar mechanisms that underlie the brain's ability to estimate and cancel self-generated vestibular (inner ear balance) input during active movement Second, we will determine how the cerebellum encodes changes in the relationship between expected and actual sensory input when these predictions are learned, adapted, and flexibly implemented. Third, we will assess how cerebellum-mediated vestibular reafference suppression generalizes to another natural self-motion behavior, namely standing balance and its adaptation. The brain's ability to distinguish sensory stimuli that are the result of…

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