NIH R01 · 2024
Decoding brain circuit underlying metabolic regulation of sleep-wake behavior
Project Summary / Abstract Sleep disorders and obesity are inextricably linked – poor sleep quality and short sleep duration increase the risk of developing obesity, while obesity is an independent risk factor for chronic sleep disruption (CSD) and excessive daytime sleepiness (EDS). Despite a clear bidirectional and pernicious association between obesity and sleep disorders, the neural substrates mediating this association remain largely unknown. Our research program seeks to identify critical neural circuit linking metabolic alterations to CSD and EDS. Our long-term goal is to delineate the neural circuits underlying metabolic regulation of sleep-wake behavior. We have recently found that…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.