NIH R01 · 2024
Prelimbic somatostatin peptide signaling in binge ethanol consumption
Project Summary Alcohol Use Disorder (AUD) is a complex psychiatric disorder with large societal and personal strain, involving many brain regions and cell types. Few effective treatments exist that specifically target the prevention of binge drinking. Understanding the underlying neurobiology of binge drinking is essential for preventing and treating this major public health problem. Ongoing work in our lab seeks to understand how somatostatin (SST) expressing GABAergic neurons in the prelimbic (PL) cortex, which have long been implicated in other neuropsychiatric disorders as an anti-depressive, resilience-conferring population of peptidergic neurons, may function as a therapeutic target…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.