Cronin Lab

Ohio State University

INTERNAL MEDICINE/MEDICINE

Columbus · United States

NIH-funded
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NIH R01 · 2025

Delivering Patient-Facing Evidence-Based Guidelines through mHealth to Adults with Sickle Cell Disease (PF-Guide)

PROJECT SUMMARY We propose a multi-center hybrid type I effectiveness-implementation trial to assess patient-facing evidence- based guidelines through a mHealth application plus (+) booklets in adults with sickle cell disease (SCD). Clinicians’ care of SCD is informed by evidence-based guidelines, which target the prevention of morbidity and mortality. The National Heart, Lung, and Blood Institute (NHLBI) and the American Society of Hematology (ASH) published guidelines for evidence-based management of SCD for healthcare providers. However, patient, provider, or system barriers prohibit adequate reach within and across all three domains, leading to poor guideline adherence. Our prior work…

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