NIH R01 · 2024
GM65440 Supplement Project Summary The element iron plays an enormous role in biology, including electron transport reactions (ferredoxins), oxygen transport and storage (hemoglobin and myoglobin), catalysis (nitrogenase, P-450, hydrogenase, and thousands of other enzymes), small molecule sensing (especially O2, CO, and NO), and DNA processing and repair. The health-relatedness of a better understanding of the structure and function of biological Fe is clear. The general theme of research in the Cramer lab involves the use spectroscopy as a tool for characterization of metals in biological systems. Much of this work involves the application of synchrotron radiation x-ray sources. Thanks to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.