NIH R01 · 2025
Endothelial Reactive Oxygen Species in Exercise Metabolism
PROJECT SUMMARY Exercise is a powerful strategy to improve skeletal muscle metabolism that can both prevent and reverse disease. However, the complex signaling that drives the immediate and long-term changes in muscle metabolism is incompletely understood. Skeletal muscle consists of multiple cell types, such as myocytes, vascular endothelial cells, pericytes, and immune cells. When subjected to exercise stress, these cells communicate with one another to coordinate the heightened energy production required by the skeletal muscle. Our long-term goal is to understand intercellular skeletal muscle signaling initiated in response to exercise, thus informing strategies to promote health and…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.