NIH R01 · 2025
In Vitro to In Vivo Extrapolation of Toxicant Effects on Ovarian Function
PROJECT SUMMARY Approximately 7.5 million American women are unable to become pregnant or carry a baby to term (impaired fecundity). The ovary is considered a critical target organ in infertility cases based on the large number of women seeking infertility treatment who are unable to release a viable egg from their ovaries. Folliculogenesis is the process through which ovarian follicles, the functional units of the ovary, develop into a form capable of sustaining hormone production and ovulating a healthy egg for fertilization. Any environmental exposure that causes damage to the ovarian follicle has the potential to impair fecundity in women. Most of what is known about toxicity to ovarian…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.