NIH R01 · 2024
PROJECT SUMMARY The toxic metal cadmium (Cd) is one of the top ten chemicals of major public health concern identified by the World Health Organization. Cd exerts toxic effects on the kidneys, respiratory and skeletal systems, and long- term exposure is associated with metabolic, cardiovascular and behavioral disorders. We and others have shown that exposure to Cd during early life can lead to disease in adulthood. One of these diseases is non- alcoholic fatty liver disease (NAFLD), characterized by fat accumulation, inflammation and tissue damage in the liver. NAFLD affects 30-40 % of the US adult population, and patients with NAFLD have a higher risk of developing liver cancer. The broad,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.