NIH R01 · 2025
Mechanisms of Glial Interactions and Function at Neuronal Cell Bodies
PROJECT SUMMARY/ABSTRACT All major mammalian glial subtypes of the central nervous system (CNS) make direct contacts with neuronal cell bodies; however, how glia support and communicate with neuronal somas is vastly understudied compared to glial interactions at synapses or axons. The overarching goal of this project is to gain a deep mechanistic understanding of glial development, communication, and function at neuronal cell bodies to begin to fill in the gaps of how these associations regulate CNS health and dysfunction. Drosophila glia demonstrate remarkable similarity to a number of mammalian glial subtypes measured by morphological, functional, and molecular criteria. Among these is…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.