Castro Lab

Sloan-Kettering Inst Can Research

New York · United States

NIH-funded
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NIH R01 · 2025

Pilot Feasibility of DESCANSO: Cognitive Behavioral Therapy for Latino Cancer Patients to Treat the Symptom Cluster Depression, Insomnia and Fatigue

PROJECT SUMMARY Symptoms of depressed mood, insomnia, and fatigue (DIF) frequently co-occur in cancer patients and Latinos report higher symptom burden than non-Latino white cancer patients. When cancer patients experience these symptoms as a cluster, they lead to more severe burden and poorer quality of life, than do the symptoms individually. Notably, the onset of one symptom can trigger others in this cluster,6 underscoring the importance of treating initial symptoms (e.g., insomnia/fatigue) to prevent the onset of others (e.g., depressed mood). This proposal aims develop and pilot a CBT intervention, DESCANSO (Depresión/Depression, Cansancio/Fatigue, and Sueño/Sleep; Rest in English) to…

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