NIH R01 · 2025
Hippocampal adult-born neurons in social memory circuits
PROJECT SUMMARY Severe social impairment is a shared symptom of many neuropsychiatric illnesses. In particular, deficits in the ability to recognize and remember previously encountered individuals—often called social memory—can significantly compromise an individual’s ability to form and maintain social relationships, dramatically reducing quality of life. Among the brain regions associated with social impairment, the hippocampus is notable due to its essential role in social memory and its exceptional structural plasticity, including the continuous generation of new neurons in the dentate gyrus throughout adulthood. Harnessing naturally occurring structural plasticity in the hippocampus…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.