NIH R01 · 2025
Cholinergic influence on visual cognitive processing
PROJECT SUMMARY/ABSTRACT Impairment in visual attention and working memory is common across mental illnesses and neurological conditions. Cholinergic drugs (acetylcholine agonists and acetylcholinesterase inhibitors) can ameliorate these symptoms, though their effectiveness is limited. An alternative way of improving cholinergic function is to stimulate the endogenous source of acetylcholine in the cerebral cortex, the Nucleus Basalis of Meynert. Recent results have shown the effectiveness of the approach in improving performance in working memory and attention tasks. However, the neuronal mechanisms of action in cortical areas involved in these processes are not yet understood. This…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.