Cone Lab

University of Delaware

BIOMEDICAL ENGINEERING

Newark · United States

NIH-funded
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NIH R01 · 2025

Importance of muscle-subtendon units in Achilles tendinopathy

Project Summary Achilles tendinopathy is a prevalent and painful condition that hinders physical activity, with a significant incidence in the general population. Current treatments primarily involve calf-strengthening exercises, but success rates vary, leading to persistent symptoms in many patients. The Achilles tendon is composed of three subtendons twisted into a bundle and each linked to one of three individual muscles in the triceps surae, with each subtendon-muscle unit serving a distinct function. This intricate anatomy – which has yet to be considered in the development of treatment options for tendinopathy – may explain the varied responses to treatment. This study aims to explore…

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