Conda Sheridan Lab

University of Nebraska Medical Center

OTHER BASIC SCIENCES

Omaha · United States

NIH-funded
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Research focus

NIH R01 · 2025

Theory Assisted Design, Synthesis and Biological Activity of Bacteria-Targeting Nanostructures

Project Summary/Abstract The goal of this project is to develop nanostructures that are selective for bacteria and to create a theoretical framework (in silico model) that can be used to predict the activity of nanostructures and their behavior and interactions with bacteria. Bacterial infections are a serious health problem that affects the human population. Further, the emergence of resistant bacterial strains has made the problem even more serious. Two pathogens of particular concern are Staphylococcus aureus and Acinetobacter baumannii. These pathogens are a main cause of nosocomial skin and lung infections and are prevalent in immunocompromised patients and hospital settings. To deal…

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