NIH R01 · 2025
Mechanisms Contributing to Pregnancy-induced Cardiac Remodeling
Maternal healthcare in the US continues to rank poorly in comparison to other developed countries. Maternal mortality rates in US have been increasing yearly, accounting for 23.8 deaths per 100,000 live births in 2020. Cardiovascular complications are the leading cause of death in pregnant and postpartum women; however, little is known regarding the underlying factors leading to this increase, which has been hindered by the lack of knowledge of how the heart responds to normal pregnancy. Despite this, it is known that during pregnancy, the heart adapts to meet the increased metabolic demands of maternal organs and the growing fetus. This adaptation is characterized by reversible cardiac…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.