Cohen Lab

University of Cincinnati

INTERNAL MEDICINE/MEDICINE

Cincinnati · United States

NIH-funded
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Research focus

NIH R01 · 2024

Towards optimizing diabetes management and diagnosis by personalizing HbA1c targets

Hemoglobin A1c (HbA1c) is used as the cornerstone indicator of blood sugar monitoring to prevent diabetic complications and hypoglycemia. However, HbA1c has limitations including unexplained racial differences, and clinically significant mismatches between HbA1c and average glucose (AG). In the context of its limitations, improvements in convenience, cost and accuracy of continuous glucose monitoring (CGM) devices have caused a reexamination of the future role for HbA1c. However, CGM glucose data is 1) a challenge to interpret, 2) more invasive than a spot blood sample, and 3) of uncertain complications risk. Bergenstal, Beck and colleagues recently proposed a Glucose Management Indicator…

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