NIH R01 · 2024
The Gut Microbiome Brain Axis and Preterm Infants
PROJECT SUMMARY Infancy is increasingly being recognized as a key time point of microbiome establishment that impacts neonatal health as well as later outcomes. The intestinal microbiome has specifically been implicated in neurologic outcomes via the gut-brain axis. However, means by which the intestinal microbiome can have influence on the brain are poorly understood. The preterm infant is at the nexus of these unknowns. Preterm infants are a vulnerable patient population at risk for significant poor long-term neurodevelopmental outcomes. Preterm infant brain development occurs in parallel with intestinal microbiome development, thus modification of the intestinal microbiome is a potential…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.