NIH R01 · 2025
PROJECT SUMMARY [18F]FDG PET is a key imaging approach used regularly for the diagnosis, staging, and identification of recurrences of various cancer types including lung, colorectal, and esophageal cancers. Studies have also shown that decreases in tumor [18F]FDG accumulation can function as a biomarker of drug efficacy. [18F]FDG PET is well-studied at the level of bulk cell populations, but studies of [18F]FDG accumulation at the level of individual cells that could yield information on cell subpopulations are lacking. Studies of cancer cell genomes and transcriptomes at the level of individual cells demonstrate important heterogeneity and subpopulations in bulk cell populations.…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.