NIH R01 · 2024
Neural Basis of Spatial Memory Deficits After Prenatal Alcohol Exposure
PROJECT SUMMARY/ABSTRACT Fetal Alcohol Spectrum Disorders are a set of major morphological, neurobiological, and cognitive abnormalities in offspring exposed to alcohol in utero. A common cognitive manifestation of alcohol exposure during neural development in humans, and in animal models of prenatal alcohol exposure (PAE), are deficits in spatial learning and memory. In moderate PAE, which accounts for the most common and underestimated form of PAE, spatial deficits are marked by an inability to accurately discriminate between spatial locations or recall previously learned spatial relationships. Systems-level monitoring of neural populations in the hippocampal formation has unraveled a…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.