NIH R01 · 2025
Determining the Sources of Motor-Cortex Response Complexity
PROJECT ABSTRACT Motor cortex is the brain area most responsible for voluntary movement. In humans, damage to motor cortex or its outputs – for example due to stroke or disease – causes profound and often permanent movement deficits. Treating dysfunction, or finding ways to bypass it, requires a principled understanding of normal function. Fundamental to that goal is the need to characterize the relationship between motor-cortex neural activity and movement. Attempts to do so must contend with a striking feature of motor cortex neural responses: their complexity and heterogeneity. Motor cortex responses are floridly multiphasic and remarkably diverse. Each recorded neuron has a unique…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.