Christou Lab

University of Florida

PHYSIOLOGY

Gainesville · United States

NIH-funded
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NIH R01 · 2024

ADVANCING THALAMIC NEUROSTIMULATION FOR SUPPRESING ESSENTIAL VOICE TREMOR

PROJECT SUMMARY Essential voice tremor (EVT) affects over 40% of individuals with essential tremor (ET), one of the most common movement disorders. While ET is characterized primarily by upper limb tremor, EVT is a significant problem because it profoundly disturbs communication and quality of life. Unfortunately, EVT remains poorly treated and the few available treatments, such as propranolol and botulinum toxin injections, have limited efficacy. Deep brain stimulation (DBS) of the ventral intermedius nucleus (VIM) of the thalamus is the treatment of choice for severe upper limb tremor no longer responding to medication. There is evidence that patients undergoing successful DBS therapy for…

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