NIH R01 · 2024
PROJECT SUMMARY Neurocognitive impairment (NCI) affects up to 50% of persons living with HIV (PWH), including individuals with well-controlled infection. Biological sex is an important determinant of NCI among PWH. The strongest available evidence indicates that women with HIV have greater cognitive deficits globally than men with HIV and, most prominently, in learning, memory, and processing speed. Although women make up half of the world’s HIV population, few studies have focused on the mechanisms underlying sex differences in the prevalence and pathogenesis of NCI in PWH, despite the consequences that these differences could have on developing distinct therapeutic approaches to NCI for…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.