Choi Lab

Research focus

NIH R01 · 2024

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

Project summary Treatment of severe obsessive-compulsive disorder (OCD) with deep brain stimulation (DBS) is evolving to provide precision modulation of pathological brain circuits. One promising DBS target for OCD is a large and complex white matter fiber bundle called the anterior limb of the internal capsule (ALIC). A clear challenge to effective dissemination of this treatment is the lack of specificity in targeting the necessary and sufficient ALIC pathways. To prepare DBS for broad dissemination, we must build the knowledge and tools to enhance the precision with which stimulation is applied to individual brains. The overarching hypothesis of the proposed research is that DBS-mediated…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.