NIH R01 · 2024
Elucidating neural mechanisms underlying sickness behaviors
ABSTRACT Sickness behaviors represent a range of behavioral changes that manifest in response to infection or inflammation. These changes include reduced physical activity, diminished social interaction, and altered feeding behavior. It is suggested that these behavioral shifts are integral to the body's immune response against pathogens, serving to conserve energy, deprive pathogens of nutrients, and contain the infection within the host's community. Nevertheless, the mechanisms behind the initiation of sickness behaviors at the level of neurons and neural circuits remain largely unexplored. This research endeavors to fill this knowledge gap by identifying a neural substrate that acts as a…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.