NIH R01 · 2024
Chronic Alcohol Exposure and Pathophysiology of Alzheimer's Disease.
Project Summary Repeated and excessive alcohol consumption is known to lead to brain damage, and may increase the risk of developing Alzheimer’s Disease (AD). A recent study demonstrated that light-to-moderate alcohol consumption, as low as eight drinks a week, may be associated with cognitive decline and AD. Not surprisingly, alcohol consumption appears to be more harmful to the elderly. Since alcohol metabolism rates decline with age, it could have a greater effect and may exacerbate underlying cognitive problems. However, the limitation of these epidemiological studies includes their observational nature without a mechanistic investigation of the “cause and effect” on how alcohol may…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.