NIH R01 · 2025
Immunopathogenesis of Adenovirus Keratitis
PROJECT SUMMARY Conjunctivitis, a common ocular condition with a range of etiologies, is highly prevalent, affecting approximately 6 million people annually in the United States, accounting for 1% of all primary care office visits, and costing 430 million USD annually. Viruses are responsible for ~ 80% of conjunctivitis cases, and human adenoviruses (HAdVs) are implicated in up to 65%. A particularly severe variant of adenoviral conjunctivitis, epidemic keratoconjunctivitis (EKC) is caused principally by viruses within human adenovirus species D (HAdV-D), for example the highly virulent adenovirus type 37. The clinical manifestations of EKC include severe membranous conjunctivitis and…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.