NIH R01 · 2025
Defining and treating genetic abnormalities in psoriasis/atopic dermatitis-overlap dermatoses
Defining and treating genetic abnormalities in psoriasis/atopic dermatitis-overlap dermatoses Project Summary/Narrative Immunomodulatory therapies now robustly improve cases of the inflammatory skin diseases psoriasis and atopic dermatitis, based on selective targeting of cytokine pathways. However, no biomarkers are available to diagnose or predict treatment regimens for the frequent, ambiguous rashes harboring overlapping clinicopathologic features of both diseases. The objective of this proposal is to use high-resolution, quantitative biomarkers specific for psoriasis and atopic dermatitis to understand the etiology of these overlap cases, which we term “PSO-AD” rashes. We will also use…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.