Chinchilli Lab

Research focus

NIH R01 · 2025

Diabetes RElated to Acute Pancreatitis and its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics (DREAM-ON)

ABSTRACT / PROJECT SUMMARY Background: Acute pancreatitis (AP) is a common and serious condition, accounting for more than 300,000 hospitalizations and over $2 billion in health care costs per year in the United States alone. Patients with AP have an increased risk of several complications including diabetes (DM). Two recent meta-analyses suggest that AP increases risk of DM by 23-37%, and that the risk increases over time. The pathogenesis of DM following AP has historically been ascribed to the loss of β-cell mass, however other mechanisms, including the development of insulin resistance or β-cell autoimmunity may also play a role. The Type 1 Diabetes and Acute Pancreatitis Consortium…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.