NIH R01 · 2024
Molecular Mechanisms of Atrial Fibrillation: A Multimodal Analysis
Abstract Atrial fibrillation (AF) is the most common arrhythmia especially in the aging population. It is associated with increased risk of mortality and morbidity. At the present time, management of AF has focused on risk factor modification, rate or rhythm control and anticoagulation. Evolution of clinical trials in the management of AF have revealed that ablation seems superior in reducing the burden of AF and controlling the symptoms compared to pharmaceutical agents. However, the benefit of ablation decreases over time and patients frequently require more than one ablation. Earlier ablation in the course of the disease is more beneficial as failure of therapy is related to duration of…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.