Chi Lab

University of California, San Diego

INTERNAL MEDICINE/MEDICINE

La Jolla · United States

NIH-funded
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NIH R01 · 2024

Mechanisms of Juxta-Cardiac Field Progenitors

Project Summary The heart is composed of a broad range of diverse cardiac cell types, which organize into distinct cardiac structures that coordinately regulate cardiac function and circulation throughout the body. Despite efforts devoted toward understanding how these cardiac cell types are created in order to develop potential human cardiac therapies and/or illuminate underlying mechanisms/etiologies of congenital heart disease (CHD), our understanding of how diverse cardiac cell types emerge from developmental heart field progenitors, and how they organize into heart structures remains to be fully defined. Thus, we propose to identify and investigate the cardiovascular developmental…

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