Chestek Lab

University of Michigan at Ann Arbor

BIOMEDICAL ENGINEERING

Ann Arbor · United States

NIH-funded
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NIH R01 · 2024

Improving hand kinematic predictions from implanted EMG in humans and monkeys

Project Summary There are millions of people worldwide with debilitating upper limb amputations. While electrical signals from residual muscle can provide some function, every amputee is missing muscles, and therefore missing a variety of important functions. Our group has demonstrated a novel method for obtaining signals from independent nerve fascicles in humans, which we call the Regenerative Peripheral Nerve Interface (RPNI). The small muscle grafts degenerate, regenerate, revascularize, and reinnervate utilizing natural biologic processes. They also introduce a degree of conformity among prosthetic users, for example always having thumb muscles available for electromyography (EMG). Our…

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