Cheng Lab

Boston University (Charles River Campus)

ENGINEERING (ALL TYPES)

Boston · United States

NIH-funded
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NIH R01 · 2024

High-content High-speed Chemical Imaging of Metabolic Reprogramming by Integration of Advanced Instrumentation and Data Science

Project Summary: Providing molecular fingerprint vibration information and high imaging speed, coherent Raman scattering microscopy, based on either coherent anti-Stokes Raman scattering (CARS) or stimulated Raman scattering (SRS), allows real-time vibrational imaging of living cells and/or tissues with sub-micron spatial resolution These instrumentation-based advances, however, do not fulfill all the desired parameters in hyperspectral imaging, including broad bandwidth, high signal to noise ratio (SNR) and high speed. In pushing these physical limits, it is common that one parameter is optimized at the price of sacrificing other advantages. The current proposal aims to break this…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.

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