NIH R01 · 2025
Novel protein biomarkers of youth-onset type 2 diabetes
PROJECT SUMMARY The effective treatment of youth-onset type 2 diabetes (YOT2D), with rising rates and an aggressive disease course that causes morbidity and mortality in young adulthood, is a healthcare priority. Our ability to develop treatments, however, is limited by our incomplete understanding of what drives this rapid progression. Proteomics has emerged as an innovative method for adult-onset type 2 diabetes (T2D) biomarker identification that can elucidate biological pathways contributing to disease or that can be affected by it, but it has not been widely used to study youths. We propose to complete comprehensive proteomics profiling on plasma obtained at multiple timepoints from a…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.