Chen Lab

Children's Hosp of Philadelphia

Philadelphia · United States

NIH-funded
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NIH R01 · 2025

Neural markers of late language emergence in preschool children born very and extremely preterm

ABSTRACT Children born extremely preterm (EP; <27 weeks gestational age (GA)) and very preterm (VP; 28 – 32 weeks GA)) are at high risk of having language-related deficits [1-5] compared to term-born control (TC) children. Little is known regarding the neural mechanisms that contribute to the substantial variation in the rate of language development in EP/VP children, with no explanation why some EP/VP preschoolers with delayed language ‘catch up,’ while others receive a diagnosis of language disorder at school age. The PI’s team has extensive experience obtaining brain function (magnetoencephalography (MEG)) and brain structure (magnetic resonance imaging (MRI)) data in infants and young…

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