Chen Lab

Cornell University

CHEMISTRY

Ithaca · United States

NIH-funded
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Research focus

NIH R01 · 2025

Mechanism of extracellular electron transfer in Gram-negative bacteria

Toxic contaminants, such as heavy metals and organic compounds, pose serious health threats to sur- rounding communities. Bioremediation, which uses living organisms such as bacteria to degrade, detoxify, or remove pollutants, has emerged as an environmentally sustainable approach to cleaning up polluted sites. The Gram-negative bacterium Shewanella is capable of reducing metals like uranium and chromium to less-toxic forms as well as of degrading organic compounds through redox reaction as part of their anaerobic respiration. Leveraging the anaerobic respiration mechanism in Shewanella can thus revolutionize bioremediation and wastewater treatment technologies. The biological foundation of…

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