Chatterjee Lab

Johns Hopkins University

BIOSTATISTICS & OTHER MATH SCI

Baltimore · United States

NIH-funded
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NIH R01 · 2024

Statistical Methods for Data Integration and Applications to Genome-wide Association Studies

Abstract Large-scale epidemiologic studies, including biobanks and genome-wide association studies (GWAS), are now rapidly leading to the identification of novel risk factors for complex diseases. There is increasing opportunity to develop comprehensive models for disease risk incorporating genetic markers, other biomarkers, life-style factors and sociodemographic indicators. There are, however, major challenges as information on all of the potential risk factors are often not available in a single adequately large study. Instead, information may be available from different studies, each of which may include some subsets of the desired variables. Further, because of privacy concerns with…

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