Chang Lab

University of California Los Angeles

NEUROLOGY

Los Angeles · United States

NIH-funded
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NIH R01 · 2024

Identifying Undiagnosed Alzheimer’s Disease in Understudied Populations

Project Abstract Diagnosis of Alzheimer’s disease (AD) is crucial for individuals to pursue treatments and plan for the future. Unfortunately, AD is underdiagnosed in community settings compared to the estimated prevalence from longitudinal cohort studies. AD underdiagnosis is exacerbated in understudied populations, including Hispanic/Latino (HL) and non-Hispanic African American (NH-AfAm) groups. Mining patients’ electronic health records (EHR) using machine learning may help identify patients with undiagnosed AD. Prior studies have identified individual comorbidities associated with AD. However, patients accumulate disease conditions sequentially accumulate over time. These pathways of…

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