Chang Lab

Johns Hopkins University

INTERNAL MEDICINE/MEDICINE

Baltimore · United States

NIH-funded
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Research focus

NIH R01 · 2025

Epidemiology and Impact of the HIV, NCD, and Urbanization Syndemic in Africa

Africa bears the vast majority (69%) of the world’s current HIV infections with 26 million persons living with HIV (PLHIV). Increased access to antiretroviral therapy (ART) in Africa has markedly extended the lives of PLHIV and is shifting morbidity and mortality among PLHIV toward non-communicable diseases (NCDs), including high burden cardiopulmonary NCDs (CP-NCDs) such as congestive heart failure, hypertension, asthma, and chronic obstructive pulmonary disease. In addition, Africa is experiencing rapid urbanization with its associated increases in air pollution and changes in lifestyle and the social, structural, and health service environment. This remarkable convergence of HIV,…

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