NIH R01 · 2024
The intestinal tract is comprised of functionally different regions, each having distinct and highly selected microbiota assembled through evolutionary and ecological drivers to achieve a mutualistic relationship important to host health. However, with ever increasing shifts in environment, diet, lifestyles, and prevalent use of antibiotics it is becoming evident that perturbations of host-microbial balance affect states of health and give rise to a multitude of disorders. This recognition has fostered interest in “natural” remedies such as Fecal Microbiota Transplant (FMT) and Live Biotherapeutic Products (LBPs) to maintain or restore gut microbiota health in patients with Clostridioides…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.