Chang Lab

University of California, San Francisco

NEUROSURGERY

San Francisco · United States

NIH-funded
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Research focus

NIH R01 · 2024

Spatiotemporal dynamics of the human emotion network

ABSTRACT Affective symptoms are a common feature of neuropsychiatric disorders that reflect dysfunction in a distributed brain network that supports emotion. How aberrant functioning in a single emotion network underlies a wide range of affective symptoms, such as depression and anxiety, is not well understood. Anchored by the anterior cingulate cortex and ventral anterior insula, the emotion network responds to numerous affective stimuli. A more sophisticated understanding of how the emotion network produces emotions—and how atypical emotion network functioning relates to affective symptoms—will be critical for advancing current neuroanatomical models of neuropsychiatric disorders.…

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