Chang Lab

Research focus

NIH R01 · 2025

A Type 2 Hybrid Effectiveness-Implementation Study of Time Limited Trials to Reduce Potentially Non-Beneficial Treatments for Critically Ill Patients with Advanced Medical Illnesses

Project Summary Overutilization of invasive intensive care unit (ICU) treatments for patients with advanced medical illnesses may lead to medical care that provides minimal benefit and prolongs suffering. Although the factors that lead to overuse of potentially non-beneficial treatments are complex, an important contributor is poor communication between clinicians, patients and surrogate decision makers. Time limited trials (TLT) involve detailed discussions of patients’ preferences for care and prognosis followed by agreements between clinicians and patients/surrogate decision-makers to use certain medical therapies for defined periods of time. TLTs promote regular structured dialogue…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.