Abel Lab

Northwestern University

OTHER HEALTH PROFESSIONS

Chicago · United States

NIH-funded
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NIH R01 · 2025

Cortical contributions to frequency-following response generation and modulation

ABSTRACT: Frequency-following responses (FFRs) are scalp-recorded electrophysiological ‘neurophonic’ potentials that reflect phase-locked activity from neural ensembles across the auditory pathway. FFRs provide a neural snapshot of the integrity of supra-threshold speech processing that can be measured non-invasively using a minimal electrophysiological set-up that already exists in audiology clinics, has high test-retest reliability, and requires minimal subject preparation. The original project, titled “Online modulation of auditory brainstem responses to speech”, examined the extent to which FFRs, which were thought to primarily reflect subcortical auditory processing, were influenced by…

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