NIH R01 · 2025
Insula-BNST Circuit Regulation of AUD
PROJECT SUMMARY Alcohol use disorder (AUD) afflicts millions of individuals and their families. Current treatment options and clinical diagnostic tools are limited, necessitating more research on the progression from casual use to AUD in certain individuals. Identifying pre-AUD biomarkers, as is common practice with heart disease and diabetes, could impact millions of lives. However, addiction involves complex overlapping patterns that complicate pinpointing cause and effect, or quantifiable biomarkers, creating an inherent pitfall. Neuronal circuits are the basic functional units that encode behavior. A better understanding of the neurocircuits engaged prior to dependence could shift…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.