Celedon Lab

University of Pittsburgh at Pittsburgh

PEDIATRICS

Pittsburgh · United States

NIH-funded
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Research focus

NIH R01 · 2025

Exposure to violence during childhood and Th2-high asthma in young Puerto Rican adults

Puerto Ricans (PRs) are disproportionately affected with asthma. We have shown that psychosocial stressors such as child maltreatment and exposure to violence (ETV) are associated with major depressive disorder (MDD) and generalized anxiety disorder (GAD), asthma, and worse asthma outcomes in PR children and adolescents. We have also demonstrated that violence-related distress is associated with reduced response to short-acting bronchodilators, and that increased violence-related distress over time is associated with worse lung function and asthma-related quality of life in PR and non-PR children and adolescents. More recently, we found that high ETV and high violence-related distress are…

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