NIH R01 · 2024
Impact of protein and alkali supplementation on skeletal muscle in older adults
PROJECT SUMMARY Skeletal muscle loss and impairment – prominent features of the aging process – lead to physical disability. There is plausible evidence that altering components of the diet, mainly protein intake and acid/base balance, may improve indices of muscle health in older adults and thus translate to a reduction in physical disability. A growing number of studies suggest that increasing protein intake using a whey protein supplement may benefit muscle health in older adults. However, a main concern is that high protein results in a large dietary acid load from the breakdown of protein to acidogenic byproducts, which could in turn promote muscle degradation particularly in older…
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