NIH R01 · 2025
Biophysical and Neural Basis of Focused Ultrasound Stimulation
This proposal responds to BRAIN Initiative RFA-NS-20-006 and aims to elucidate the neural and biophysical mechanisms of noninvasive focused ultrasound (FUS) neuromodulation. FUS overcomes shortcomings of other neuromodulation methods and can noninvasively stimulate millimeter-scale regions in any part of the brain including deep brain structures. We seek to understand how different doses and spatiotemporal applications of FUS interact with the brain at cellular, circuit, and behavioral level. When used in conjunction with MRI, the FUS beam can be precisely localized while network-level effects can be observed with BOLD fMRI. In the past few years, through BRAIN Initiative funded projects,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.