NIH R01 · 2024
Pathophysiology Informed Biomarkers of Treatment Response in Early Psychosis (PIB)
The introduction of Coordinated Specialty Care (CSC) has transformed the standard of care and elevated treatment outcome goals for young individuals experiencing the initial stages of a psychotic illness (EP). The response to treatment for EP individuals receiving CSC, however, remains highly variable. A substantial proportion show minimal symptom reduction despite receiving the full range of evidence-based practices comprising this treatment model. Currently, clinicians have no way to predict which EP individuals entering CSC will respond to treatment and published data show that expert clinicians perform no better than chance. Early identification of treatment non-responders has very high…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.